安裝黃金價格查詢,金價報價工具!
安裝黃金價格查詢,金價報價工具!
安裝黃金價格查詢,金價報價工具!
|
- Organoids: A new window into disease, development and discovery
Organoids can range in size from less than the width of a hair to five millimeters There are potentially as many types of organoids as there are different tissues and organs in the body To date, researchers have been able to produce organoids that resemble the brain, kidney, lung, intestine, stomach, and liver, and many more are on the way
- Improved human brain organoids to boost neurological disease research
These advances mean that brain organoids can now be used as viable experimental systems to study diseases in patient tissues directly, and to compare different drug effects on human brain tissues After one month of growing in the lab, a brain organoid contains clusters of cells that will develop into neurons
- Improving skin organoids | Harvard Stem Cell Institute (HSCI)
The organoids also produced Merkel cells, specialized touch-responsive cells of the skin that have been implicated in diseases such as Merkel cell carcinoma “The inclusion of these other cell types likely expands the potential uses of the skin organoid model to research on sensory disorders and cancer,” she added
- Brain organoids replicate key events in human brain development . . .
Evaluating models Organoids are particularly useful for studying human development, where standard approaches used to study other animals can’t be used But some scientists have previously questioned whether a brain organoid’s culture dish could serve as a realistic stand-in for the complex milieu of the human brain
- Engineered miniature kidneys come of age - Harvard University
Mini-organs, called organoids, are grown in a culture dish They contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, intestine, and brain Organoids have the potential to transform drug discovery, allowing researchers to experiment on samples of human tissue grown directly from patients The challenge Because organoids are grown outside of a
- Paola Arlotta, Ph. D. | Harvard Stem Cell Institute (HSCI)
Building on this work in the embryo, we have more recently pioneered the development of stem cell-derived brain organoids that model the human cortex, to study previously-inaccessible mechanisms of human neurodevelopment and disease
- Cyborg brain organoids offer insight into early brain development
Since their development more than a decade ago, brain organoids — brain-like structures grown in petri dishes from human stem cells — have helped scientists better understand a range of neurological disorders, including schizophrenia, epilepsy, and autism spectrum disorders
- Using organoids to study early-stage lung cancer
HSCI researchers develop organoids to model cancer and test potential treatments Lung organoids made from mouse lung stem cells, with a cancer-initiating mutation in the KRAS gene (green) Credit: Antonella Dost, Boston Children’s Hospital Lung cancer, the leading cancer killer in the U S , is often missed in its earlier stages
|
|
|